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The BASE facility, at The University Of Queensland, is a global leader in mRNA research and manufacture.
We help scientists develop new mRNA medicines. We have experience building mRNA for a wide range of clinical applications.
We provide end-to-end research services to design, manufacture and test new mRNA medicines.
BASE is a global leader in mRNA research. Our scientists are leading innovative research programs in:
BASE scientists have experience designing mRNAs for a wide range of clinical applications.
Our software toolkit, mRNArchitect, can optimise your mRNA sequences for expression, stability and immunogenicity.
We have also assembled a catalog of validated elements, including UTRs, localisation and signal peptides.
BASE can manufacture mRNA medicines according to your specification, including:
Our mRNA and LNPs is carefully tested to ensure high quality, purity and performance.
BASE has established a validated platform to build high-quality mRNAs. Each step, from intial sequence design, mRNA synthesis and LNP formulation, has been optimised to ensure mRNA quality and performance.
We have built hundreds of mRNAs using this approach, that been extensively validated in different cell-types and applications. Our expert team can provide helpful support at each step.
We stock a range of off-the-shelf mRNAs that provide useful controls during experiments, including:
These catalog mRNAs can be shipped immediately.
We can help develop mRNA medicines from discovery, pre-clinical through to early clinical outcomes. We can tailor our research services to your requirements, including:
Our support team is available to help with your mRNA projects.