mRNA-LNP services
Small-scale mRNA for in vitro studies
- Ideal for cell-culture studies
- Custom design and optimisation according to specification
- Full mRNA Design Report
- Validated mRNA backbone (UTRs + poly(A) tail)
- Cell-free DNA template
- Small-scale (~100ug) mRNA synthesis
- Cellulose purification
- Full quality control report
- Protocols for transfection into different cells available
Large-scale mRNA for in vivo studies
- Ideal for mouse and pre-clinical studies
- Custom design and optimisation according to specification
- Full mRNA Design Report
- Validated mRNA backbone (UTRs + poly(A) tail)
- Cell-free DNA template
- Medium-scale (1mg+) mRNA synthesis
- Oligo dT Purification
- Full QC report
- Protocols for delivery and administration available
Our mRNA-LNP platform
Sequence design
- mRNArchitect software used to optimise sequence expression and stability.
- Use our experimentally-validated catalog of UTRs and mRNA elements.
- Every project accompanied by full Design Report.
- Full ownership of your mRNA sequence.
mRNA synthesis
- Approved designs are synthesised using cell-free mRNA workflow.
- Optimised production and purification to ensure high-quality mRNA.
- Every batch undergoes rigorous QC for identity, purity, and integrity.
- Additional purification and dsRNA or endotoxin testing available on request.
LNP formulation
- Diverse experience formulating mRNA into LNPs for in vivo delivery.
- Targeted LNP approaches available for delivery to specific cell types and tissues.
- Support custom formulations, including novel ionisable lipids, excipients and RNA cargoes
- Full analysis of every batch to ensure quality and performance
Enquiries
Our team is available to help with your mRNA projects.