mRNA Design

Begin with good sequence design

Building mRNA

Our design team has experience building hundreds of mRNAs that have been validated across a wide range of applications.

We can build mRNA constructs tailored to your specifications. Using our software, mRNArchitect, we assemble and optimize sequences for translation efficiency, stability, and immunogenicity.

We also offer a catalog of useful RNA elements (UTRs, signal peptides, polyA tails, etc.) that have been validated by our team.

Software

BASE scientists use mRNArchitect to design our mRNAs.

mRNArchitect optimises primary mRNA sequences against weighted criteria (including secondary structure, codons, GC and U content).

mRNArchitect is freely available for use.