mRNA Products + Services

mRNA technologies

Custom mRNAs

We can manufacture custom mRNA vaccines and therapies according to your specifications. Our end-to-end services include;

mRNA design and experimental support
Small and large-scale mRNA manufacture
Lipid nanoparticle (LNP) formulation

Our expert team can provide helpful support at each step in the design and manufacturing process.

Catalog mRNAs

We stock a range of off-the-shelf mRNAs that provide useful controls during experiments – including reporter, model antigens, and genome editing mRNAs.

These catalog mRNAs can be shipped immediately.

Quality Feature	Method
Sequence Identity	NGS, Sanger
mRNA Purity	UV Spectrophotometry
mRNA Length / Integrity	Capillary Electrophoresis
mRNA Concentration	UV Spectrophotometry
mRNA Length / Integrity	HPLC
LNP Encapsulation	Ribogreen Assay
LNP Size, Uniformity and Zeta	Dynamic Light Scattering
Endotoxins	LAL Assay
Appearance	Visual Inspection

Quality Control

All of our mRNA and LNP batches undergo rigorous testing that is provided in the accompanying quality control report.

Our validated assays can measure critical mRNA quality attributes, including identity, purity, yield, contamination and integrity.

Consistent quality control ensures the reliability of mRNA and reproducibility of your experiments.

mRNA Analytics

BASE provides comprehensive analytical services supported by a quality control team with experience analysing hundreds of diverse mRNAs.

We can also provide mRNA validation services in cell-culture, including protein expression and immune response.

Our analytical services are available to support stability, characterisation and method development studies.

Enquiries

Our support team is available to help with your mRNA projects.