Targeting LNPs for cell-specific delivery of mRNA

News - October 17, 2024


The targeted delivery of mRNA therapeutics remains a major challenge in treating disease.

BASE scientists have published a method in Molecular Therapy – Nucleic Acids that directs mRNA–LNPs to specific cells and tissues using bispecific antibodies that bind mRNA–LNPs to cell-surface receptors.

Latest news from BASE


4th QLD mRNA Symposium

On International RNA Day (1 August), the BASE facility hosted the 4th QLD mRNA Symposium, bringing together leading experts from research, clinical, government, and industry to discuss advances in mRNA medicines.

mRNA-LNP masterclass

Our graduates successfully completed the first Winter mRNA Masterclass, a week-long intensive program that trains students in the science, computational design, and laboratory production of mRNAs and LNPs.

Our workflow published

We published our step-by-step protocol for mRNA-LNP production, describing the design, manufacture, and quality control of mRNA medicines using standard equipment in a research laboratory.

Enquiries

Our team is available to help with your mRNA projects.