BASE facility partners with DNA Script to integrate SYNTAX Platform and Enzymatic DNA Synthesis Technology into mRNA vaccine manufacture.
SOUTH SAN FRANCISCO, Calif., and PARIS, April 12, 2022 — The BASE facility has partnered with DNA Script, a world leader in Enzymatic DNA Synthesis (EDS) for DNA on demand, as part of a new program to receive early access to the latest advancements of their EDS technology.
Dubbed the DNA Scriptors Early Access Program, the initiative accelerates the expansion of applications for the SYNTAX System by providing users with ongoing opportunities to access products prior to full commercial launch. New SYNTAX Platform features that will be available for early access include a new generation of kits that enable the printing of longer oligos, up to 80 nt in length, and the synthesis of probes labeled with biotin or fluorophores and quenchers.
“We have multiple development teams working to enhance all aspects of our SYNTAX Platform, from new chemistries that increase oligo mass, length and quality as well as enable modifications, to new instrument models and upgrades that increase plex,” said DNA Script CEO and co-founder Thomas Ybert. “Feedback from over 40 alpha and beta collaborators was critical to a successful launch of the SYNTAX System in June 2021, and this DNA Scriptors program ensures that we continue to innovate with the needs of our customers in mind.”
Located within UQ’s Australian Institute for Bioengineering and Nanotechnology (AIBN), the BASE facility provides genetic material to advance Australian research and is particularly focused on developing anti-cancer and other vaccines. “DNA Script’s SYNTAX System allows us to quickly synthesize DNA according to our precise requirements, which is critical for the manufacture of mRNA vaccines and therapies, ” said Tim Mercer, Ph.D., BASE Director and Assistant Professor at AIBN. “Being part of the DNA Scriptors Early Access Program provides access to this leading technology needed to speed the manufacture of mRNA vaccines. This access will enable rapid response to emerging infectious diseases and support the development of personalized vaccines in cancer.”
The SYNTAX Platform is a paradigm shift that empowers labs to produce DNA on demand, thanks to the world’s first benchtop enzymatic DNA printer. The system is built around EDS, which synthesizes DNA oligos like nature does, making it a much simpler, faster and greener process than older phosphoramidite chemistry-based approaches.
About DNA Script
Founded in 2014, DNA Script is a pioneering life sciences technology company developing a new, faster, more powerful and versatile way to design and manufacture nucleic acids. The company has developed an alternative to traditional DNA synthesis called Enzymatic DNA Synthesis, or EDS, enabling this technology to be accessible to labs with the first benchtop enzymatic synthesis instrument, the SYNTAX System. By putting DNA synthesis back in the lab, DNA Script aims to transform life sciences research through innovative technology that gives researchers unprecedented control and autonomy. www.dnascript.com